💪 Your PrEP, Your Power: Top Choices for Men Who Want to Stay HIV-Negative
- Jose Iorio

- Jul 28
- 3 min read

In Brooklyn and beyond, men are taking charge of their sexual health like never before—and PrEP is leading the revolution. Whether you're gay, straight, bi, trans, curious, monogamous, poly, or somewhere in between—there’s a PrEP option made for you.
Pre-exposure prophylaxis (PrEP) is safe, effective, and FDA-approved. When taken correctly, it reduces the risk of HIV from sex by up to 99%. And now, you’ve got options: daily pills, on-demand PrEP, and long-acting injectables.
Let’s break it down so you can choose the best fit for your life, body, and vibe.
🧠 What Is PrEP—and Why Should Men Consider It?
PrEP stands for pre-exposure prophylaxis. It’s HIV prevention in the form of medication. If you’re HIV-negative and sexually active—especially with multiple partners or inconsistent condom use—PrEP adds a powerful layer of protection.
It’s not about who you are or how you identify—it’s about owning your sexual wellness. Here’s who should consider it:
✔️ Men who have sex with men (MSM)✔️ Men in mixed-status relationships (HIV-positive partner)✔️ Men who don't always use condoms✔️ Men who hook up with partners of unknown HIV status✔️ Men who love sex and want to stay safe doing it
💊 PrEP Pills: Truvada vs. Descovy
Truvada: The OG, Tried-and-True
Truvada has been preventing HIV since 2012. It’s taken once a day, and works great for most men.
Why you might love it:
Proven effectiveness with years of real-world data
Available as a generic = more affordable
Great for all genders and most bodies
Heads up:
May slightly affect kidney function or bone density over time
Not ideal if you already have kidney or osteoporosis concerns
Descovy: Sleek, Newer, Gentler
Approved in 2019, Descovy is a little easier on the kidneys and bones. It’s also once-daily, but currently only approved for cisgender men and trans women.
Why guys choose Descovy:
Lower risk of kidney/bone side effects
Same high protection level as Truvada
Clean, modern formulation
Limitations:
Not approved for people at risk from receptive vaginal sex
May cost more, depending on coverage
💉 Don’t Like Pills? Meet Injectable PrEP
Apretude is a long-acting PrEP injection you get every two months. It's discreet, simple, and perfect for guys who don’t want to worry about daily pills.
It’s already changing the game for:
Men with busy lives or who struggle with daily routines
Anyone who wants to “set it and forget it”
Guys who want maximum privacy or discretion
🔁 On-Demand PrEP: For the “Only-When-I-Need-It” Type
This option—sometimes called PrEP 2-1-1—is ideal for cis men who have sex with men and want protection only around times of sex.
How it works:
2 pills 2–24 hours before sex
1 pill 24 hours later
1 pill 48 hours later
Not for vaginal sex or inconsistent routines—but great for occasional sex or weekends only.
🛑 Is PrEP Just for Bottoms?
Nope. Let’s bust that myth right now.
PrEP works regardless of sexual position. Whether you're a top, bottom, or versatile—it protects you by stopping HIV from establishing itself in your body.
Real talk:✔️ Tops can benefit just as much as bottoms✔️ PrEP is for oral sex, rough sex, group sex, or spontaneous sex✔️ If your sex life is adventurous, PrEP belongs in your toolkit
🧬 So… Which PrEP Is Right for You?
Your body. Your life. Your decision.
Here’s how to choose your perfect match:
🔹 Talk to a provider. They’ll run labs, talk risk, and walk you through it.🔹 Have kidney or bone concerns? Ask about Descovy.🔹 Want to ditch daily pills? Try injectable Apretude.🔹 Only have sex occasionally? PrEP-on-demand might work for you.🔹 No insurance? No problem. We’ll help you get covered.
🌍 Beyond Just Pills: PrEP + More = Total Protection
PrEP is a boss move—but pair it with these for best results:
Condoms for extra STI protection
Regular STI testing (at least every 3 months)
Honest convos with partners
DoxyPEP to prevent syphilis, chlamydia, and gonorrhea
🎯 Ready to Get On PrEP in Brooklyn?
We got you.
📍 STAR Health Center
470 Clarkson Ave, Suite J, Brooklyn, NY🕘 Mon–Wed 9AM–5PM | Thu 1:30PM–5PM | Fri 9AM–5PM
📞 Call/Text: 347-909-1680🌐 www.GetMeOnPrEP.com🌐 www.starprogram.nyc
✨ Walk in with questions. Walk out protected. ✨


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