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The Only Twice-a-Year Injectable HIVPrEP Is Here

A groundbreaking step in HIV prevention has arrived. The U.S. Food and Drug

Administration (FDA) has approved Yeztugo® (lenacapavir) — the first and only

long-acting injectable PrEP administered twice a year — for use in adults and

adolescents weighing at least 35kg (77 lbs). Backed by clinical success and designed

for convenience, this innovative option is changing how we approach HIV prevention.

What Is Yeztugo® (lenacapavir)?


Yeztugo® is a twice-a-year injectable form of pre-exposure prophylaxis (PrEP) — a preventative medication designed to protect people who are HIV-negative from acquiring the virus through sex. Unlike daily pills or every-2-month injections, Yeztugo® only requires two injections a year, making it the most infrequent PrEP regimen available today.




Fast Facts:

Feature Details

Name: Yeztugo® (lenacapavir)

Type: Injectable PrEP

Frequency: Twice a year (every 6 months)

Approved For Adults and adolescents ≥ 35kg

Effectiveness: 99.9% HIV prevention rate in trials




Who Can Use Yeztugo®?


It is indicated for any HIV-negative adult or adolescent aged 12+ who weighs at least

35kg (77lbs) and is at risk for sexually acquired HIV. It is beneficial for:


  • People who struggle with taking daily oral PrEP

  • Youth who prefer fewer healthcare touchpoints

  • Individuals seeking a discreet or private prevention method


Availability in New York

Yeztugo® is now available by prescription. If you live in New York, you can talk to your PrEP provider or visit an NYC Sexual Health Clinic to learn more. Many clinics,

including the STAR Health Center in Brooklyn, offer HIV prevention services,

including PrEP, PEP, and now Yeztugo®.


Need help getting started?

No insurance? No worries. Call/text 347-909-1680 or visit www.GetMeOnPrEP.com

for free support, appointments, and access to prevention tools near you


What About the Cost?

Yeztugo® can be covered by most insurances, with prior approval. However, if you are uninsured/underinsured, there are programs available to assist with cost. Always speak with a provider, social worker, or navigator about cost-assistance options.


Final Take: Why Yeztugo® Matters

This isn't just a new option — it's a game-changer for HIV prevention. By reducing the dosing to twice a year, it removes barriers to access, simplifies adherence, and brings us closer to ending the epidemic (ETE).


Ready to take control of your sexual health on your terms?

Ask about Yeztugo®…

...Stay protected……Stay empowered.

Get Started Today!!


STAR Health Center – Brooklyn

470 Clarkson Ave, Suite J

Mon-Wed 9am–5pm | Thurs 1:30–5pm | Fri 9am–5pm

Call or text: 347-909-1680


Sources:

 Gilead – Yeztugo® (Lenacapavir) FDA Announcement  CDC – HIV Prevention and PrEP Guidelines

 New York State Department of Health – PrEP Resources

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