The Only Twice-a-Year Injectable HIVPrEP Is Here
- Jose Iorio

- 4 hours ago
- 2 min read
A groundbreaking step in HIV prevention has arrived. The U.S. Food and Drug
Administration (FDA) has approved Yeztugo® (lenacapavir) — the first and only
long-acting injectable PrEP administered twice a year — for use in adults and
adolescents weighing at least 35kg (77 lbs). Backed by clinical success and designed
for convenience, this innovative option is changing how we approach HIV prevention.
What Is Yeztugo® (lenacapavir)?
Yeztugo® is a twice-a-year injectable form of pre-exposure prophylaxis (PrEP) — a preventative medication designed to protect people who are HIV-negative from acquiring the virus through sex. Unlike daily pills or every-2-month injections, Yeztugo® only requires two injections a year, making it the most infrequent PrEP regimen available today.

Fast Facts:
Feature Details
Name: Yeztugo® (lenacapavir)
Type: Injectable PrEP
Frequency: Twice a year (every 6 months)
Approved For Adults and adolescents ≥ 35kg
Effectiveness: 99.9% HIV prevention rate in trials
Who Can Use Yeztugo®?
It is indicated for any HIV-negative adult or adolescent aged 12+ who weighs at least
35kg (77lbs) and is at risk for sexually acquired HIV. It is beneficial for:
People who struggle with taking daily oral PrEP
Youth who prefer fewer healthcare touchpoints
Individuals seeking a discreet or private prevention method
Availability in New York
Yeztugo® is now available by prescription. If you live in New York, you can talk to your PrEP provider or visit an NYC Sexual Health Clinic to learn more. Many clinics,
including the STAR Health Center in Brooklyn, offer HIV prevention services,
including PrEP, PEP, and now Yeztugo®.
Need help getting started?
No insurance? No worries. Call/text 347-909-1680 or visit www.GetMeOnPrEP.com
for free support, appointments, and access to prevention tools near you
What About the Cost?
Yeztugo® can be covered by most insurances, with prior approval. However, if you are uninsured/underinsured, there are programs available to assist with cost. Always speak with a provider, social worker, or navigator about cost-assistance options.
Final Take: Why Yeztugo® Matters
This isn't just a new option — it's a game-changer for HIV prevention. By reducing the dosing to twice a year, it removes barriers to access, simplifies adherence, and brings us closer to ending the epidemic (ETE).
Ready to take control of your sexual health on your terms?
Ask about Yeztugo®…
...Stay protected……Stay empowered.
Get Started Today!!
STAR Health Center – Brooklyn
470 Clarkson Ave, Suite J
Mon-Wed 9am–5pm | Thurs 1:30–5pm | Fri 9am–5pm
Call or text: 347-909-1680
Sources:
Gilead – Yeztugo® (Lenacapavir) FDA Announcement CDC – HIV Prevention and PrEP Guidelines
New York State Department of Health – PrEP Resources




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