Doxy-PEP: Protect Yourself Against STIs—and Don’t Forget About PrEP
- Jose Iorio
- Mar 2
- 3 min read
Hey Brooklyn fam, let’s talk about something that can help keep your sexual health game strong!
The CDC now recommends doxycycline as post-exposure prophylaxis (Doxy-PEP) to help prevent certain bacterial STIs if you’ve had recent unprotected sex or other high-risk exposure. Best of all, Doxy-PEP pairs perfectly with HIV PrEP (pre-exposure prophylaxis) when you’re looking for that extra layer of protection.
Below, we’ll break down the basics on how Doxy-PEP works, why pairing it with PrEP matters, and what you need to know before you start. If you’re ready to chat with a friendly provider about your options, book a consultation now or keep reading for the details!
Doxy-PEP: The Lowdown
What Is Doxy-PEP?
Doxy-PEP means taking 200 mg of doxycycline as soon as possible (within 72 hours) after you’ve had sex.
Why bother? The CDC says it can help you cut down your risk of certain bacterial STIs, like chlamydia, gonorrhea, and syphilis.
How to Take It
Timing: One 200 mg dose within 72 hours. Don’t exceed 200 mg in a 24-hour period.
With Food & Water: Take it with food and at least 8 ounces of water to protect your stomach.
Wait to Lie Down: Avoid lying down for at least an hour after taking doxy.
Skip Dairy & Certain Supplements: Don’t take doxy within two hours of having dairy, antacids, or anything with iron, calcium, or magnesium.
Cover Up: Doxy makes your skin more sensitive to sunlight, so wear sunscreen or a hat if you’re heading outside.
Possible Side Effects
Sun Sensitivity
Upset Stomach
Diarrhea
Irritated Throat
If you’re feeling any of these symptoms and you’re worried, reach out to our team. We’ll get you answers and help keep you on track.
Why Doxy-PEP and PrEP Are a Power Duo
Looking to prevent HIV, too? Consider adding PrEP to your routine. Here’s why they work so well together:
After Doxy-PEP: If you test negative for HIV, it’s a good time to explore PrEP.
Ongoing Prevention: Doxy-PEP helps reduce bacterial STIs; PrEP helps prevent HIV. When you combine them, you’re covering more bases.
Recommended for MSM & TGW: If you’re a man who has sex with men (MSM) or a transgender woman (TGW), regular HIV screening and prevention can make a real difference.
Not sure where to start? Schedule a free consultation to talk about your sexual health goals. We’ll help you figure out if you’re a good fit for PrEP, Doxy-PEP, or both.
Follow-Up Care (Because Health Is Ongoing)
Routine Testing: Get tested for STIs and HIV every 3 to 6 months. Consistency is key!
Reassess Doxy-PEP: Discuss with your healthcare provider every 3 to 6 months if continuing Doxy-PEP is right for you.
Stay in the Know: Pay attention to updates, keep the conversation going with your provider, and stay open to any new guidelines.
We know talking about sexual health can sometimes feel awkward, but we promise—we’ve got your back. We’re here to help you navigate your options and give you the info you need to make the best choices for your body.
Take Control of Your Sexual Health Today
Ready to dive deeper? Here’s how you can take the next step:
Check Your Eligibility: Find out if Doxy-PEP or PrEP is a fit for your lifestyle.
Book an Appointment: Talk with our providers about your concerns, goals, and anything in between.
Get in Touch: Send us your questions. We love hearing from you!
We’re all about keeping Brooklyn (and beyond) healthy, informed, and ready for whatever comes next. If you want to learn more about Doxy-PEP, PrEP, or any other sexual health topics,
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